Hydrochloric Acid → HCID 68065988、化合物

HRID 594947ノート

反応式

HRID 594947 の反応式
C(O)C.[N:4]1[CH:5]=[CH:6][N:7]2[CH:12]=[C:11]([C:13]3[C:17]4[CH2:18][N:19](C(OC(C)(C)C)=O)[CH2:20][CH2:21][C:16]=4[NH:15][N:14]=3)[CH:10]=[CH:9][C:8]=12.Cl>O1CCOCC1>[N:4]1[CH:5]=[CH:6][N:7]2[CH:12]=[C:11]([C:13]3[C:17]4[CH2:18][NH:19][CH2:20][CH2:21][C:16]=4[NH:15][N:14]=3)[CH:10]=[CH:9][C:8]=12

参加物

5

反応物 3

HCID 313Hydrochloric AcidHCID 702Ethanol2 回HCID 68065989HCID 68065989、化合物

生成物 1

HCID 68065988HCID 68065988、化合物

試薬・触媒・溶媒 1

HCID 312751,4-Dioxane溶媒

実験手順

In a flask, ethanol (1 mL) was added to tert-butyl 3-(imidazo[1,2-a]pyridin-6-yl)-6,7-dihydro-1H-pyrazolo[4,3-c]pyridine-5(4H)-carboxylate (0.750 g, 0.0022 mol). Hydrochloric acid in dioxane (4 M, 8 mL) was added to the reaction and was stirred for 30 minutes. Ethanol (5 mL) was added to the reaction, and the resulting solution was concentrated in vacuo. The crude product was progressed to the next step without further purification.

後処理

  1. concentrationthe resulting solution was concentrated in vacuo
  2. customThe crude product was progressed to the next step without further purification

出典と根拠

ORDレコード
ord-e429da4b082344478720ab47bfa103fd
出典データセット
uspto-grants-2016_01
特許番号
US09242981B2

反応ノート

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