化工社化工社 化学情報印刷レポート · 研究参考用
Ethanol → Ethyl 4-chlorobutyrate
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Ethanol | HCID 702 | — |
| 反応物 | 4-Chlorobutanoic acid | HCID 12300 | — |
| 反応物 | Thionyl Chloride | HCID 24386 | — |
| 生成物 | Ethyl 4-chlorobutyrate | HCID 18474 | — |
反応手順
SOCl2 (60.0 mL, 820 mmol) was added to a solution of 4-chloro-butyric acid (50.0 g, 410 mmol) in EtOH (1.2 L) at 0° C. The mixture was heated to reflux for 2 hr then cooled to room temperature and concentrated under reduced pressure to afford the crude 4-chloro-butyric acid ethyl ester.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US09242984B2 |
| 出典データセット | uspto-grants-2016_01 |
| ORD ID | ord-917bd02f027c47efa868f43de331fd4b |
| 出典メモ | uspto-grants-2016_01 |