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2,6-Dimethylaniline → N-(1,3-dioxolan-5-ylmethyl)-2,6-dimethylaniline
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | 2,6-Dimethylaniline | HCID 6896 | — |
| 反応物 | Potassium Carbonate | HCID 11430 | — |
| 反応物 | 4-(Chloromethyl)-1,3-dioxolane | HCID 240153 | — |
| 触媒 | Tetraethylammonium Chloride | HCID 5946 | — |
| 生成物 | N-(1,3-dioxolan-5-ylmethyl)-2,6-dimethylaniline | HCID 21447788 | — |
反応手順
2,6-Dimethylaniline (94.5 grams), 5-chloromethyl-1,3-dioxolane (31.8 grams), potassium carbonate (36.7 grams) and tetraethylammonium chloride (2 grams) were charged into a glass reaction vessel equipped with a mechanical stirrer, thermometer and reflux condenser. The reaction mixture was heated at reflux for a period of 48 hours. After this time the mixture was filtered and distilled to yield the desired product N-(1,3-dioxolan-5-ylmethyl)-2,6-dimethylaniline having a boiling point of 132° C under aspirator pressure.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US04012222 |
| 出典データセット | uspto-grants-1977_03 |
| ORD ID | ord-23f0f4f0891e4bd1890a83ba2bd6d841 |
| 出典メモ | uspto-grants-1977_03 |