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Potassium Carbonate → N-(1,3-dioxolan-5-ylmethyl)-2,6-dimethyl-4-bromoaniline
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Potassium Carbonate | HCID 11430 | — |
| 反応物 | 4-Bromo-2,6-xylidine | HCID 90549 | — |
| 反応物 | 4-(Chloromethyl)-1,3-dioxolane | HCID 240153 | — |
| 触媒 | Tetraethylammonium Chloride | HCID 5946 | — |
| 生成物 | N-(1,3-dioxolan-5-ylmethyl)-2,6-dimethyl-4-bromoaniline | HCID 21447802 | — |
反応手順
2,6-Dimethyl-4-bromoaniline (0.3 mole), 5-chloromethyl-1,3-dioxolane (0.3 mole), potassium carbonate (0.3 mole) and tetraethylammonium chloride (2 grams) are charged into a glass reaction vessel equipped with a mechanical stirrer, thermometer and reflux condenser. The reaction mixture is heated at reflux for a period of 5 hours. After this time the mixture is filtered and distilled to yield the desired product N-(1,3-dioxolan-5-ylmethyl)-2,6-dimethyl-4-bromoaniline.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US04012222 |
| 出典データセット | uspto-grants-1977_03 |
| ORD ID | ord-7817933fbf3f446c876e88053d9ca1f2 |
| 出典メモ | uspto-grants-1977_03 |