化工社化工社 化学情報印刷レポート · 研究参考用
Water → 2-Propenenitrile, 3-(4-fluorophenyl)-
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Water | HCID 962 | — |
| 反応物 | Hydroxyamine hydrochloride | HCID 443297 | — |
| 反応物 | Sodium Formate | HCID 2723810 | — |
| 反応物 | 3-(4-Fluorophenyl)-2-propenal | HCID 53384379 | — |
| 溶媒 | Formic Acid | HCID 284 | — |
| 生成物 | 2-Propenenitrile, 3-(4-fluorophenyl)- | HCID 367324 | 70.4% |
反応手順
p-Fluorocinnamaldehyde (9.0 g.) was refluxed for 1 hr. in 98% formic acid containing sodium formate (10 g.) and hydroxylamine hydrochloride (7 g.). The solution was cooled and poured into water (275 ml.), giving a solid. This was washed well with water, leaving p-fluorocinnamonitrile (6.21 g., 70%), m.p. 64°-65°, λmax. (EtOH) 271 nm ε 22500.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US04012377 |
| 出典データセット | uspto-grants-1977_03 |
| ORD ID | ord-e9949bbebf3b423f8e3963e521514c62 |
| 出典メモ | uspto-grants-1977_03 |