4-Methyl-2-nitrobenzaldehyde → trans-2,2'-Dinitro-4-methylstilbene

HRID 597138ノート

反応式

HRID 597138 の反応式
C[O-].[Na+].[N+:4]([C:7]1[CH:14]=[C:13]([CH3:15])[CH:12]=[CH:11][C:8]=1[CH:9]=O)([O-:6])=[O:5]>C(O)C>[N+:4]([C:7]1[CH:14]=[C:13]([CH3:15])[CH:12]=[CH:11][C:8]=1/[CH:9]=[CH:9]/[C:8]1[CH:11]=[CH:12][CH:13]=[CH:14][C:7]=1[N+:4]([O-:6])=[O:5])([O-:6])=[O:5]

参加物

4

反応物 2

HCID 5904464-Methyl-2-nitrobenzaldehydeHCID 10942334Sodium Methoxide

生成物 1

HCID 21446813trans-2,2'-Dinitro-4-methylstilbene収率 85%

試薬・触媒・溶媒 1

HCID 702Ethanol溶媒2 回

実験手順

In a solution of 1.4 g. of sodium methylate in 40 ml. of ethanol, 6.8 g. of diethyl ortho-nitrobenzyl phosphonate was dissolved. While stirring the solution at ambient temperature, a solution of 4.1 g. of 2-nitro-4-methylbenzaldehyde in 40 ml. of ethanol was dropwise added. After being stirred for 1.5 hours and allowed to stand overnight, the yellow crystals formed were filtered and washed with a small amount of ethanol to give 6.0 g. (85% yield) of trans-2,2'-dinitro-4-methylstilbene melting at 170° to 171° C. (recrystallized from benzene).

後処理

  1. stirringAfter being stirred for 1.5 hours
  2. customthe yellow crystals formed
  3. filtrationwere filtered
  4. washwashed with a small amount of ethanol
  5. customto give 6.0 g

出典と根拠

ORDレコード
ord-783d1e96a3b04f468c8964bc1aafbdd2
出典データセット
uspto-grants-1977_03
特許番号
US04013639

反応ノート

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