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Hydrochloric Acid → HCID 178503824、化合物
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Hydrochloric Acid | HCID 313 | — |
| 反応物 | Cysteamine Hydrochloride | HCID 9082 | — |
| 反応物 | 1,1-Bis(methylthio)-2-nitroethylene | HCID 83623 | — |
| 反応物 | Picrate | HCID 4432340 | — |
| 反応物 | HCID 178479151 | HCID 178479151 | — |
| 反応物 | HCID 178511470 | HCID 178511470 | — |
| 生成物 | HCID 178503824 | HCID 178503824 | — |
反応手順
Reaction of 2-amino-4-hydroxymethylimidazole hydrochloride (which is obtained by treating the picrate salt with hydrochloric acid) with cysteamine hydrochloride and reaction of the resulting 2-amino-4-[(2-aminoethyl)-thiomethyl]imidazole with 1-nitro-2,2-bis-methylthioethylene according to the procedure of Example 8(i) gives 1-nitro-2-methylthio-2-[2-((2-amino-4-imidazolyl)methylthio)-ethylamino]ethylene. Finally, reaction with 2-[(2-aminoethyl)thiomethyl]-3-chloropyridine by the procedure of Example 1 (a)(ii) produces the title compound.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US04013769 |
| 出典データセット | uspto-grants-1977_03 |
| ORD ID | ord-b1c6cfb86095455ab6118d489d5799bb |
| 出典メモ | uspto-grants-1977_03 |