Sulfuric Acid → HCID 178421831、化合物

HRID 597606ノート

反応式

HRID 597606 の反応式
N([C:8]1[C:9](=[O:21])[C:10]2[C:15]([C:16](=[O:18])[CH:17]=1)=[CH:14][C:13]([CH3:19])=[C:12]([CH3:20])[CH:11]=2)C1C=CC=CC=1.S(=O)(=O)(O)[OH:23]>O>[CH3:19][C:13]1[CH:14]=[C:15]2[C:10](=[CH:11][C:12]=1[CH3:20])[C:9](=[O:21])[C:8]([OH:23])=[CH:17][C:16]2=[O:18]

参加物

4

反応物 2

HCID 1118Sulfuric AcidHCID 12369068HCID 12369068、化合物

生成物 1

HCID 178421831HCID 178421831、化合物

試薬・触媒・溶媒 1

HCID 962Water溶媒2 回

実験手順

A solution of 2-anilino-6,7-dimethyl-1,4-naphthoquinone (3.1; 0.014 mole) in concentrated sulphuric acid (70ml) was diluted with an equal volume of water and refluxed for 1 minute. After pouring into cold water the precipitated hydroxy derivative was filtered off and extracted into petrol ether (b.p. 100°-102° C). After treatment of the extract with charcoal the title compound separated as a yellow solid, 1.29g (55%), m.p. 175°-177° C (d). (Found; C, 71.29; H, 5.07; C12H10O3 requires; C, 71.28; H, 4.98%)

後処理

  1. temperaturerefluxed for 1 minute
  2. filtrationwas filtered off
  3. extractionextracted into petrol ether (b.p. 100°-102° C)
  4. extractionAfter treatment of the extract with charcoal the title compound
  5. customseparated as a yellow solid, 1.29g (55%), m.p. 175°-177° C (d)

出典と根拠

ORDレコード
ord-cac5ba4f4a7d41dd81b0221c1600af2b
出典データセット
uspto-grants-1977_03
特許番号
US04014907

反応ノート

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