化工社化工社 化学情報印刷レポート · 研究参考用
Fenbufen → 7-Phenyl-1-tetralone
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Fenbufen | HCID 3335 | — |
| 反応物 | 4-{[1,1'-Biphenyl]-4-yl}butanoic acid | HCID 11139230 | — |
| 生成物 | 7-Phenyl-1-tetralone | HCID 3778235 | 30% |
反応手順
4-(4'-Biphenylyl) butanoic acid (80g, 0.333 mole m.p. 116° C prepared by the Clemmensen reduction of 3-(4'-biphenylcarbonyl) propanoic acid) was cyclized with 85% polyphosphoric acid as described in example 8(a) to give 20.98g (30%) of the tetralone m.p. 67° C after recrystallisation from 40-60 petrol. (Found; C, 86.30; H, 6.53, C16H14O requires; C, 86.45; H, 6.35%).
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US04014907 |
| 出典データセット | uspto-grants-1977_03 |
| ORD ID | ord-5a01d01e27cd4ed489b94a510e377d62 |
| 出典メモ | uspto-grants-1977_03 |