Acetyl chloride → 1-Oxaspiro[4.5]decan-6-ol, 2,6,10,10-tetramethyl-, 6-acetate

反応式

[CH3:1][CH:2]1[CH2:6][CH2:5][C:4]2([C:11]([CH3:13])([CH3:12])[CH2:10][CH2:9][CH2:8][C:7]2([CH3:15])[OH:14])[O:3]1.[C:16](Cl)(=[O:18])[CH3:17]>>[C:16]([O:14][C:7]1([CH3:15])[CH2:8][CH2:9][CH2:10][C:11]([CH3:13])([CH3:12])[C:4]21[O:3][CH:2]([CH3:1])[CH2:6][CH2:5]2)(=[O:18])[CH3:17].[CH:16]([O:14][C:7]1([CH3:15])[CH2:8][CH2:9][CH2:10][C:11]([CH3:13])([CH3:12])[C:4]21[O:3][CH:2]([CH3:1])[CH2:6][CH2:5]2)=[O:18]

参加物

反応物 2

HCID 6367Acetyl chloride

HCID 654286-Hydroxydihydrotheaspirane

生成物 2

HCID 938381-Oxaspiro[4.5]decan-6-ol, 2,6,10,10-tetramethyl-, 6-acetate

HCID 23346561HCID 23346561、化合物

実験手順

2,6,10,10-Tetramethyl-1-oxa-spiro[4.5]dec-6-yl acetate was prepared as indicated hereinabove, from 2,6,10,10-tetramethyl- 1-oxa-spiro[4.5]decan-6-ol and acetyl chloride. 2,6,10,10-Tetramethyl-1-oxa-spiro[4.5]dec-6-yl formate on the contrary was obtained by treating the above alcohol with formylimidazole, according to the method given in Liebigs Ann. Chem. 655, 95 (1962).

出典と根拠

ORDレコード: ord-64a6f52819a54718ba21714b865e3195
出典データセット: uspto-grants-1977_03
DOI: 10.6084/m9.figshare.5104873.v1
特許番号: US04014905

反応ノート

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