化工社化工社 化学情報印刷レポート · 研究参考用
p-Tolylacetonitrile → 5-[2-(2,4-Difluoro-phenyl)-2H-pyrazol-3-yl]-3-p-tolyl-benzo[c]isoxazole
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | p-Tolylacetonitrile | HCID 76280 | — |
| 反応物 | 1-(2,4-difluoro-phenyl)-5-(4-nitro-phenyl)-1H-pyrazole | HCID 90033224 | — |
| 生成物 | 5-[2-(2,4-Difluoro-phenyl)-2H-pyrazol-3-yl]-3-p-tolyl-benzo[c]isoxazole | HCID 73050955 | — |
反応手順
The title compound, light yellow solid (13 mg, 10%), MS (ISP) m/z=388.2 [(M+H)+], mp 147° C., was prepared in accordance with the general method of example 1 from 1-(2,4-difluoro-phenyl)-5-(4-nitro-phenyl)-1H-pyrazole (intermediate I) (100 mg, 353 μmol) and commercially available 2-(p-tolyl)-acetonitrile.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US09440962B2 |
| 出典データセット | uspto-grants-2016_09 |
| ORD ID | ord-3f1c34642f704789aef1248c772f4bca |
| 出典メモ | uspto-grants-2016_09 |