化工社化工社 化学情報印刷レポート · 研究参考用
2-Aminothiazole → 1-[2-(2-Methoxy-benzoyl)-4-methyl-phenyl]-3-thiazol-2-yl-urea
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | 2-Aminothiazole | HCID 2155 | — |
| 反応物 | 2-Amino-5-methylbenzoic acid | HCID 76255 | — |
| 反応物 | (2-Amino-5-methyl-phenyl)-(2-methoxy-phenyl)-methanone | HCID 66998824 | — |
| 生成物 | 1-[2-(2-Methoxy-benzoyl)-4-methyl-phenyl]-3-thiazol-2-yl-urea | HCID 59733095 | 72% |
| 生成物 | (2-Amino-5-methyl-phenyl)-(2-methoxy-phenyl)-methanone | HCID 66998824 | 35% |
反応手順
(2-Amino-5-methyl-phenyl)-(2-methoxy-phenyl)-methanone (843 g, 35%) was prepared from 2-amino-5-methyl-benzoic acid (1.51 g, 0.1 mol) following the general procedure S. 1-[2-(2-methoxy-benzoyl)-4-methyl-phenyl]-3-thiazol-2-yl-urea (132 mg, 72%) was prepared from (2-amino-5-methyl-phenyl)-(2-methoxy-phenyl)-methanone (121 mg, 0.5 mmol) and 2-aminothiazole (0.060 g, 0.6 mmol) following the general procedure D.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US07897628B2 |
| 出典データセット | uspto-grants-2011_03 |
| ORD ID | ord-86e0d6d365f046459d7b5ef576f7d67d |
| 出典メモ | uspto-grants-2011_03 |