Phenylhydrazine → 3-tert-butyl-1-phenyl-1H-pyrazol-5-amine

反応式

[C:1]1([NH:7][NH2:8])[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.[CH3:9][C:10]([CH3:17])([CH3:16])[C:11](=O)[CH2:12][C:13]#[N:14]>>[C:10]([C:11]1[CH:12]=[C:13]([NH2:14])[N:7]([C:1]2[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=2)[N:8]=1)([CH3:17])([CH3:16])[CH3:9]

参加物

反応物 2

HCID 7516Phenylhydrazine

HCID 108871Pentanenitrile, 4,4-dimethyl-3-oxo-

生成物 1

HCID 7706343-tert-butyl-1-phenyl-1H-pyrazol-5-amine

実験手順

Phenyl hydrazine and 4,4-dimethyl-3-oxopentanenitrile were combined according to literature procedures to yield 3-tert-butyl-1-phenyl-1H-pyrazol-5-amine. See WO 2006/071940.

出典と根拠

ORDレコード: ord-85c6be8f36d74604b32ca244bbba600e
出典データセット: uspto-grants-2011_03
DOI: 10.6084/m9.figshare.5104873.v1
特許番号: US07897762B2

反応ノート

読み込み中…