2-Amino-5-bromobenzenesulfonamide → N-[2-(aminosulfonyl)-5-chlorothien-3-yl]-1-benzyl-4-hydroxy-2-oxo-1,2-dihydroquinoline-3-carboxamide

HRID 601169

反応式

HRID 601169 の反応式
[NH2:1][C:2]1[CH:6]=[C:5]([Cl:7])[S:4][C:3]=1[S:8]([NH2:11])(=[O:10])=[O:9].NC1C=CC(Br)=CC=1S(N)(=O)=O.[CH2:24]([N:31]1[C:40]2[C:35](=[CH:36][CH:37]=[CH:38][CH:39]=2)[C:34]([OH:41])=[C:33]([C:42](OCC)=[O:43])[C:32]1=[O:47])[C:25]1[CH:30]=[CH:29][CH:28]=[CH:27][CH:26]=1>>[NH2:11][S:8]([C:3]1[S:4][C:5]([Cl:7])=[CH:6][C:2]=1[NH:1][C:42]([C:33]1[C:32](=[O:47])[N:31]([CH2:24][C:25]2[CH:30]=[CH:29][CH:28]=[CH:27][CH:26]=2)[C:40]2[C:35]([C:34]=1[OH:41])=[CH:36][CH:37]=[CH:38][CH:39]=2)=[O:43])(=[O:9])=[O:10]

参加物

4

反応物 3

HCID 8207002-Amino-5-bromobenzenesulfonamideHCID 109559343-Amino-5-chlorothiophene-2-sulfonamideHCID 54711837Ethyl 1-benzyl-4-hydroxy-2-oxo-1,2-dihydroquinoline-3-carboxylate

生成物 1

HCID 67063731N-[2-(aminosulfonyl)-5-chlorothien-3-yl]-1-benzyl-4-hydroxy-2-oxo-1,2-dihydroquinoline-3-carboxamide

実験手順

The title compound is prepared according to the procedure of Example 84C substituting the product of Example 174A for the product of Example 84A and substituting the product of Example 99A for the product of example Example 84B.

出典と根拠

ORDレコード
ord-28bde75c0e594c23bc7208f753ae7cbe
出典データセット
uspto-grants-2011_03
特許番号
US07902203B2

関連ノート

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