Acetylthiourea → N-[5-(3-fluoro-4-methylsulfonylphenyl)-4-methyl-1,3-thiazol-2-yl]acetamide

HRID 601611

反応式

HRID 601611 の反応式
[F:1][C:2]1[CH:3]=[C:4]([CH2:12][C:13](=O)[CH3:14])[CH:5]=[CH:6][C:7]=1[S:8]([CH3:11])(=[O:10])=[O:9].[C:16]([NH:19][C:20]([NH2:22])=[S:21])(=[O:18])[CH3:17]>>[F:1][C:2]1[CH:3]=[C:4]([C:12]2[S:21][C:20]([NH:19][C:16](=[O:18])[CH3:17])=[N:22][C:13]=2[CH3:14])[CH:5]=[CH:6][C:7]=1[S:8]([CH3:11])(=[O:10])=[O:9]

参加物

3

反応物 2

HCID 2723593AcetylthioureaHCID 573512781-(3-Fluoro-4-(methylsulfonyl)phenyl)propan-2-one

生成物 1

HCID 57351276N-[5-(3-fluoro-4-methylsulfonylphenyl)-4-methyl-1,3-thiazol-2-yl]acetamide

実験手順

This material is prepared from 1-(3-fluoro-4-methanesulfonyl-phenyl)-propan-2-one (AA3) following the procedure outlined in step (AA4), replacing thiourea with N-acetylthiourea. The titled compound crystallises from the reaction mixture.

後処理

  1. customThe titled compound crystallises from the reaction mixture

出典と根拠

ORDレコード
ord-7a937789efef48928f327c332f8f97ae
出典データセット
uspto-grants-2011_03
特許番号
US07902375B2

関連ノート

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