Methacrylic Acid → 2-Methyl-4-oxatricyclo[5.2.1.02,6]decan-3-yl methacrylate

HRID 601739ノート

反応式

HRID 601739 の反応式
C(O[CH:5]1[O:13][CH2:12][CH:11]2[C:6]1([CH3:15])[CH:7]1[CH2:14][CH:10]2[CH2:9][CH2:8]1)(=O)C.[C:16]([OH:21])(=[O:20])[C:17]([CH3:19])=[CH2:18]>C(C1C(O)=C(C(C)(C)C)C=C(C)C=1)C1C(O)=C(C(C)(C)C)C=C(C)C=1>[C:16]([O:21][CH:5]1[O:13][CH2:12][CH:11]2[C:6]1([CH3:15])[CH:7]1[CH2:14][CH:10]2[CH2:9][CH2:8]1)(=[O:20])[C:17]([CH3:19])=[CH2:18]

参加物

4

反応物 2

HCID 4093Methacrylic AcidHCID 669308112-Methyl-4-oxatricyclo[5.2.1.02,6]decan-3-yl acetate

生成物 1

HCID 669307992-Methyl-4-oxatricyclo[5.2.1.02,6]decan-3-yl methacrylate収率 91%

試薬・触媒・溶媒 1

HCID 83982,2'-Methylenebis(4-methyl-6-tert-butylphenol)触媒

反応条件

温度
50 °C

実験手順

A mixture of 73 g of 2-methyl-4-oxatricyclo[5.2.1.02,6]-decan-3-yl acetate, 150 g of methacrylic acid, and 40 mg of 2,2′-methylenebis(6-t-butyl-p-cresol) was heated at 50° C. under atmospheric pressure for 30 minutes, after which under a reduced pressure of 0.20 kPa, the reaction mixture was heated for 18 hours for distilling off the acetic acid formed. The reaction mixture was purified by distillation, obtaining 72 g (yield 91%) of the target compound.

後処理

  1. temperatureafter which under a reduced pressure of 0.20 kPa, the reaction mixture was heated for 18 hours
  2. distillationfor distilling off the acetic acid
  3. customformed
  4. distillationThe reaction mixture was purified by distillation

出典と根拠

ORDレコード
ord-a4e26a2840e440c09d215439599b115c
出典データセット
uspto-grants-2011_03
特許番号
US07902385B2

反応ノート

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