化工社化工社 化学情報印刷レポート · 研究参考用
Toluene → 3,5-Difluoro-4-(2-propynyloxy)benzoyl chloride
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Toluene | HCID 1140 | — |
| 反応物 | Thionyl Chloride | HCID 24386 | — |
| 反応物 | 3,5-Difluoro-4-(2-propynyloxy)benzoic acid | HCID 57445666 | — |
| 溶媒 | Dimethylformamide | HCID 6228 | — |
| 生成物 | 3,5-Difluoro-4-(2-propynyloxy)benzoyl chloride | HCID 57445696 | — |
反応手順
To 17 ml of toluene were added 1.8 g of 3,5-difluoro-4-(2-propynyloxy)benzoic acid, 1 ml of thionyl chloride and 10 mg of DMF and the mixture was heated under reflux for 4 hours. Then, the reaction mixture was concentrated under reduced pressure to obtain 1.9 g of 3,5-difluoro-4-(2-propynyloxy)benzoyl chloride represented by the formula:
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US07902400B2 |
| 出典データセット | uspto-grants-2011_03 |
| ORD ID | ord-d638ee2f8f2f4de88ea2035df800bcc1 |
| 出典メモ | uspto-grants-2011_03 |