4-Chloro-9H-dipyrido[2,3-b;4',3'-d]pyrrole-6-carboxylic acid → 4-Chloro-9H-dipyrido[2,3-b;4',3'-d]pyrrole

HRID 60258

反応式

HRID 60258 の反応式
[Cl:1][C:2]1[C:10]2[C:9]3[CH:11]=[C:12](C(O)=O)[N:13]=[CH:14][C:8]=3[NH:7][C:6]=2[N:5]=[CH:4][CH:3]=1>CN1CCCC1.CN1C(=O)CCC1>[Cl:1][C:2]1[C:10]2[C:9]3[CH:11]=[CH:12][N:13]=[CH:14][C:8]=3[NH:7][C:6]=2[N:5]=[CH:4][CH:3]=1

参加物

4

反応物 1

HCID 583650834-Chloro-9H-dipyrido[2,3-b;4',3'-d]pyrrole-6-carboxylic acid

生成物 1

HCID 583650494-Chloro-9H-dipyrido[2,3-b;4',3'-d]pyrrole

試薬・触媒・溶媒 2

HCID 84541-Methylpyrrolidine溶媒HCID 13387N-methyl-2-pyrrolidone溶媒

実験手順

A mixture of 4-chloro-9H-dipyrido[2,3-b;4′,3′-d]pyrrole-6-carboxylic acid (390 mg, 1.57 mmol) in N-methylpyrrolidine (8 mL) was heated under reflux for 8 hours. The mixture was allowed to cool to ambient temperature. The compound was used as a solution in NMP for subsequent reactions. LCMS (Method B): RT=2.15 min, M+H+=204.

後処理

  1. temperaturewas heated
  2. temperatureunder reflux for 8 hours

出典と根拠

ORDレコード
ord-65e1ba1981d541f8b32d7f51f50d36d3
出典データセット
uspto-grants-2016_09
特許番号
US09440976B2

関連ノート

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