化工社化工社 化学情報印刷レポート · 研究参考用
Sodium Hydroxide → Pentafluorobenzenesulfonamide
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Sodium Hydroxide | HCID 14798 | — |
| 反応物 | Ammonium Chloride | HCID 25517 | — |
| 反応物 | 2,3,4,5,6-Pentafluorobenzenesulfonyl chloride | HCID 70026 | — |
| 溶媒 | Acetone | HCID 180 | — |
| 生成物 | Pentafluorobenzenesulfonamide | HCID 2063927 | 36% |
反応手順
Under room temperature, a solution of 468 g of pentafluorobenzenesulfonyl chloride in acetone was added dropwise to an aqueous solution containing 964 g of ammonium chloride, during which a pH was adjusted to 7 with an aqueous sodium hydroxide solution. The precipitated product was filtered, and recrystallized from toluene to obtain 156 g of pentafluorobenzenesulfonamide as white crystals. A structure was confirmed by 1H-NMR, 19F-NMR and IR.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US07910686B2 |
| 出典データセット | uspto-grants-2011_03 |
| ORD ID | ord-9e29f437fa32492cbe862a61782d3444 |
| 出典メモ | uspto-grants-2011_03 |