3-Amino-4-(4-methoxy-phenylsulfanyl)-benzoic acid methyl ester → 4-(4-Methoxy-phenylsulfanyl)-3-(pyrido[2,3-d]pyrimidin-4-ylamino)-benzoic acid methyl ester

HRID 605280ノート

反応式

HRID 605280 の反応式
[CH3:1][O:2][C:3](=[O:20])[C:4]1[CH:9]=[CH:8][C:7]([S:10][C:11]2[CH:16]=[CH:15][C:14]([O:17][CH3:18])=[CH:13][CH:12]=2)=[C:6]([NH2:19])[CH:5]=1.C([C:23]1[C:24]([N:29]=[CH:30][N:31]([CH3:33])C)=[N:25][CH:26]=[CH:27][CH:28]=1)#N>>[CH3:1][O:2][C:3](=[O:20])[C:4]1[CH:9]=[CH:8][C:7]([S:10][C:11]2[CH:16]=[CH:15][C:14]([O:17][CH3:18])=[CH:13][CH:12]=2)=[C:6]([NH:19][C:33]2[C:23]3[CH:28]=[CH:27][CH:26]=[N:25][C:24]=3[N:29]=[CH:30][N:31]=2)[CH:5]=1

参加物

3

反応物 2

HCID 613055833-Amino-4-(4-methoxy-phenylsulfanyl)-benzoic acid methyl esterHCID 66808319N'-(3-Cyano-pyridin-2-yl)-N,N-dimethyl-formamidine2 回

生成物 1

HCID 670406454-(4-Methoxy-phenylsulfanyl)-3-(pyrido[2,3-d]pyrimidin-4-ylamino)-benzoic acid methyl ester

実験手順

The product from Example 136B and the product from Example 29A were reacted according to the procedure from Example 136C substituting the product from Example 29A for the product from Example 8E to provide the title compound.

出典と根拠

ORDレコード
ord-63966feeb0d145779c953a9d7fbbe186
出典データセット
uspto-grants-2011_03
特許番号
US07910595B2

反応ノート

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