N-[5-(4-Hydroxy-phenylsulfanyl)-2-methyl-4-nitro-phenyl]-benzamide → N-[4-Amino-5-(4-hydroxy-phenylsulfanyl)-2-methyl-phenyl]-benzamide

HRID 605293ノート

反応式

HRID 605293 の反応式
[OH:1][C:2]1[CH:7]=[CH:6][C:5]([S:8][C:9]2[C:10]([N+:25]([O-])=O)=[CH:11][C:12]([CH3:24])=[C:13]([NH:15][C:16](=[O:23])[C:17]3[CH:22]=[CH:21][CH:20]=[CH:19][CH:18]=3)[CH:14]=2)=[CH:4][CH:3]=1.OC1C=CC(SC2C([N+]([O-])=O)=CC(C)=C(NC(=O)CC3C=CC=CC=3)C=2)=CC=1>>[NH2:25][C:10]1[C:9]([S:8][C:5]2[CH:6]=[CH:7][C:2]([OH:1])=[CH:3][CH:4]=2)=[CH:14][C:13]([NH:15][C:16](=[O:23])[C:17]2[CH:22]=[CH:21][CH:20]=[CH:19][CH:18]=2)=[C:12]([CH3:24])[CH:11]=1

参加物

3

反応物 2

HCID 67040761N-[5-(4-Hydroxy-phenylsulfanyl)-2-methyl-4-nitro-phenyl]-benzamide2 回HCID 67041085N-[5-(4-Hydroxy-phenylsulfanyl)-2-methyl-4-nitro-phenyl]-2-phenyl-acetamide

生成物 1

HCID 67040289N-[4-Amino-5-(4-hydroxy-phenylsulfanyl)-2-methyl-phenyl]-benzamide収率 100%

実験手順

The product from Example 267B was reacted according to the procedure from Example 265C substituting the product from Example 267B for the product from Example 265B to provide the title compound as a brown solid (0.11 g, 100%). This material was utilized without purification by silica gel chromatography.

出典と根拠

ORDレコード
ord-bb73e60440204624b03b795b13312e09
出典データセット
uspto-grants-2011_03
特許番号
US07910595B2

反応ノート

読み込み中…