Water → HCID 67040477、化合物

HRID 605311ノート

反応式

HRID 605311 の反応式
[CH2:1]([O:3][C:4]([C:6]1[S:7][C:8](Cl)=[C:9]([N+:11]([O-:13])=[O:12])[CH:10]=1)=[O:5])[CH3:2].[SH:15][C:16]1[CH:21]=[CH:20][C:19]([OH:22])=[CH:18][CH:17]=1.C(=O)([O-])[O-].[Cs+].[Cs+].O>CN(C)C=O>[CH2:1]([O:3][C:4]([C:6]1[S:7][C:8]([S:15][C:16]2[CH:21]=[CH:20][C:19]([OH:22])=[CH:18][CH:17]=2)=[C:9]([N+:11]([O-:13])=[O:12])[CH:10]=1)=[O:5])[CH3:2]

参加物

6

反応物 4

HCID 962WaterHCID 10796Cesium carbonateHCID 2401474-MercaptophenolHCID 56763846HCID 56763846、化合物

生成物 1

HCID 67040477HCID 67040477、化合物

試薬・触媒・溶媒 1

HCID 6228Dimethylformamide溶媒

実験手順

The product from Example 351A (1 equiv) and 4-mercaptophenol (1 equiv) were dissolved in dimethylformamide and cesium carbonate (5 equiv) added. The resultant mixture was stirred at 80° C. for 2.5 hours, cooled to room temperature and water added. The solution was extracted with ethyl acetate, the organic extracts dried and concentrated under vacuum to provide the title product.

後処理

  1. extractionThe solution was extracted with ethyl acetate
  2. customthe organic extracts dried
  3. concentrationconcentrated under vacuum

出典と根拠

ORDレコード
ord-149745779bac4c5f9a7501b9b1308c5e
出典データセット
uspto-grants-2011_03
特許番号
US07910595B2

反応ノート

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