Hydrochloric Acid → [2,4'-Bipyridine]-3-carboxylic acid dihydrochloride

HRID 60594ノート

反応式

HRID 60594 の反応式
[N:1]1[CH:6]=[CH:5][CH:4]=[C:3]([C:7]([O:9]CC)=[O:8])[C:2]=1[C:12]1[CH:17]=[CH:16][N:15]=[CH:14][CH:13]=1.[ClH:18]>>[ClH:18].[ClH:18].[N:1]1[CH:6]=[CH:5][CH:4]=[C:3]([C:7]([OH:9])=[O:8])[C:2]=1[C:12]1[CH:17]=[CH:16][N:15]=[CH:14][CH:13]=1

参加物

3

反応物 2

HCID 313Hydrochloric AcidHCID 46317743Ethyl [2,4'-bipyridine]-3-carboxylate

生成物 1

HCID 84819756[2,4'-Bipyridine]-3-carboxylic acid dihydrochloride

実験手順

A solution of ethyl 2,4′-bipyridine-3-carboxylate (14.1 g) in 6 N hydrochloric acid (200 mL) was heated under reflux overnight. The solvent was evaporated under reduced pressure, to the obtained residue was added toluene, and the solvent was again evaporated under reduced pressure to give the title compound (16.4 g).

後処理

  1. temperatureunder reflux overnight
  2. customThe solvent was evaporated under reduced pressure, to the obtained residue
  3. additionwas added toluene
  4. customthe solvent was again evaporated under reduced pressure

出典と根拠

ORDレコード
ord-cecd3cfd4c14416f843c14b787dd2b2d
出典データセット
uspto-grants-2016_09
特許番号
US09440990B2

反応ノート

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