化工社化工社 化学情報印刷レポート · 研究参考用
Diethyl Oxalate → Ethyl 6-chloro-4-oxo-3,4-dihydroquinazoline-2-carboxylate
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Diethyl Oxalate | HCID 7268 | — |
| 反応物 | 2-Amino-5-chlorobenzamide | HCID 78876 | — |
| 生成物 | Ethyl 6-chloro-4-oxo-3,4-dihydroquinazoline-2-carboxylate | HCID 135810262 | 58% |
反応手順
2-Amino-5-chlorobenzamide (2.387 g) and diethyl oxalate were stirred at 175° C. for 6 hr. The mixture was allowed to cool, and the obtained crude crystals were washed with hot ethanol to give the title compound (2.051 g, 58%).
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US07915267B2 |
| 出典データセット | uspto-grants-2011_03 |
| ORD ID | ord-35afc13731924c5e8c288c675a8e5e50 |
| 出典メモ | uspto-grants-2011_03 |