Sulfuric Acid → 2-Amino-5-nitrobenzamide
反応式
[NH2:1][C:2]1[CH:9]=[CH:8][C:7]([N+:10]([O-:12])=[O:11])=[CH:6][C:3]=1[C:4]#[N:5].S(=O)(=O)(O)[OH:14]>>[NH2:1][C:2]1[CH:9]=[CH:8][C:7]([N+:10]([O-:12])=[O:11])=[CH:6][C:3]=1[C:4]([NH2:5])=[O:14]参加物
3
反応条件
- 温度
- 130 °C
実験手順
A mixture of 2-amino-5-nitrobenzonitrile (25.4 g) and sulfuric acid (70 mL) was stirred at 130° C. for 40 min. The reaction mixture was added slowly to ice water, and the precipitate was collected by filtration, washed with water, ethanol and diethyl ether to give 2-amino-5-nitrobenzamide (24.6 g).
後処理
- filtrationthe precipitate was collected by filtration
- washwashed with water, ethanol and diethyl ether
出典と根拠
- ORDレコード
- ord-81a291086d23419792bc4437853ea22c
- 出典データセット
- uspto-grants-2011_03
- 特許番号
- US07915267B2
反応ノート
読み込み中…