1H-1,2,4-Triazole → 3-[3-(1H-1,2,4-triazol-1-yl)propoxy]benzonitrile

反応式

ClCCOC1C=C(C=CC=1)C#N.Cl[CH2:14][CH2:15][CH2:16][O:17][C:18]1[CH:19]=[C:20]([CH:23]=[CH:24][CH:25]=1)[C:21]#[N:22].[NH:26]1[CH:30]=[N:29][C:28](S)=[N:27]1.N1C=NC=N1>>[N:26]1([CH2:14][CH2:15][CH2:16][O:17][C:18]2[CH:19]=[C:20]([CH:23]=[CH:24][CH:25]=2)[C:21]#[N:22])[CH:30]=[N:29][CH:28]=[N:27]1

参加物

反応物 4

HCID 92571H-1,2,4-Triazole

HCID 135691673-(2-Chloroethoxy)benzonitrile

HCID 219940813-(3-Chloropropoxy)benzonitrile

HCID 178527894HCID 178527894、化合物

生成物 1

HCID 432891753-[3-(1H-1,2,4-triazol-1-yl)propoxy]benzonitrile

実験手順

By a method similar to that in Reference Example 2, and using, instead of 3-[(2-chloroethyl)oxy]benzonitrile, 3-[(3-chloropropyl)oxy]benzonitrile obtained in Reference Example 4 and using, instead of 1H-1,2,4-triazole-3-thiol, 1H-1,2,4-triazole, the title compound was obtained as a colorless oil (750.0 mg, 32%).