Ammonia → 2-Thiobutyrylamino-acetamide
反応式
C[O:2][C:3](=O)[CH2:4][NH:5][C:6](=[S:10])[CH2:7][CH2:8][CH3:9].[NH3:12]>CO>[C:6]([NH:5][CH2:4][C:3]([NH2:12])=[O:2])(=[S:10])[CH2:7][CH2:8][CH3:9]参加物
4
実験手順
A solution of the product of Example 5B (0.788 g, 4.496 mmol) in methanol (30 mL) was saturated with ammonia gas and the reaction was stirred in a stoppered flask at room temperature for 17 hours. The solvent was concentrated under vacuum giving the title compound and the solid purified by silica gel flash chromatography with 10% methanol/methylene chloride to give the title compound as a white solid (500 mg, 3.12 mmol, 69%).
後処理
- concentrationThe solvent was concentrated under vacuum
出典と根拠
- ORDレコード
- ord-61939e7f9b844ea7a393b37a008bc364
- 出典データセット
- uspto-grants-2011_03
- 特許番号
- US07915411B2
反応ノート
読み込み中…