Stannous Chloride → 4-(2-Amino-4-methyl-phenylsulfanyl)-phenol

反応式

[CH3:1][C:2]1[CH:7]=[CH:6][C:5]([S:8][C:9]2[CH:14]=[CH:13][C:12]([OH:15])=[CH:11][CH:10]=2)=[C:4]([N+:16]([O-])=O)[CH:3]=1.Cl[Sn]Cl>>[NH2:16][C:4]1[CH:3]=[C:2]([CH3:1])[CH:7]=[CH:6][C:5]=1[S:8][C:9]1[CH:14]=[CH:13][C:12]([OH:15])=[CH:11][CH:10]=1

参加物

反応物 2

HCID 24479Stannous Chloride

HCID 549110984-(4-Methyl-2-nitro-phenylsulfanyl)-phenol

生成物 1

HCID 668081234-(2-Amino-4-methyl-phenylsulfanyl)-phenol収率 117.5%

実験手順

The product from Example 6b (8.65 g, 31.3 mmol) was reduced with SnCl2 following the procedure from Example 5I giving the title compound as a white solid (8.51 g, 100%).

出典と根拠

ORDレコード: ord-4dc88caaca594578962ad731f143a52c
出典データセット: uspto-grants-2011_03
DOI: 10.6084/m9.figshare.5104873.v1
特許番号: US07915411B2

反応ノート

読み込み中…