化工社化工社 化学情報印刷レポート · 研究参考用
2-Bromo-5-methylbenzoic acid → rac-cis-(2-(Aminomethyl)-3-methylpiperidin-1-yl)(2-bromo-5-methylphenyl)methanone
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | 2-Bromo-5-methylbenzoic acid | HCID 228080 | — |
| 反応物 | cis-N-Boc-1-(3-methylpiperidin-2-YL)methanamine | HCID 95378400 | — |
| 生成物 | rac-cis-(2-(Aminomethyl)-3-methylpiperidin-1-yl)(2-bromo-5-methylphenyl)methanone | HCID 131737146 | — |
反応手順
The title compound was synthesized following the same general protocol as described in Example 11 using rac-cis-tert-butyl ((3-methylpiperidin-2-yl)methyl)carbamate and 2-bromo-5-methylbenzoic acid. ESI-MS (m/z): 325, 327, [M]+, [M+2]+.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US09440982B2 |
| 出典データセット | uspto-grants-2016_09 |
| ORD ID | ord-e5c8f0cc12d34483939a84bf0561aee4 |
| 出典メモ | uspto-grants-2016_09 |