関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|
| 反応物 | Aniline | HCID 6115 | — |
| 反応物 | Triethylamine | HCID 8471 | — |
| 反応物 | Benzoyl chloride, 3-nitro- | HCID 8495 | — |
| 反応物 | Sodium Bicarbonate | HCID 516892 | — |
| 溶媒 | Dichloromethane | HCID 6344 | — |
| 生成物 | 3-Nitrobenzanilide | HCID 347755 | — |
反応手順
To a cooled (0° C.) solution of aniline (17 g, 180 mmol) and triethylamine (27 mL, 190 mmol) in dichloromethane (100 mL) was added a solution of 3-nitrobenzoyl chloride (30 g, 160 mmol) in dichloromethane (60 mL). The mixture was stirred for 15 min at 0° C. then overnight at room temperature. It was then poured into saturated sodium bicarbonate (1 L) and stirred vigorously for 15 min. The precipitate was collected, washed with water and dried (40 g, 100%).
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 特許番号 | US05998463 |
|---|
| 出典データセット | uspto-grants-1999_12 |
|---|
| ORD ID | ord-68e152fdc1f3477bba21a2bec2bf8b0b |
|---|
| 出典メモ | uspto-grants-1999_12 |
|---|
