Methanol → methyl (2S)-4-methyl-2-(methylamino)pentanoate
反応式
[CH3:1][NH:2][C@H:3]([C:8]([OH:10])=[O:9])[CH2:4][CH:5]([CH3:7])[CH3:6].O1CCOC[CH2:12]1.CO>Cl>[CH3:12][O:9][C:8](=[O:10])[C@H:3]([CH2:4][CH:5]([CH3:7])[CH3:6])[NH:2][CH3:1]参加物
5
実験手順
N-methyl-L-leucine (1.3 g, 8.95 mmol) was dissolved in 4M HCl, 1,4-dioxane (10 mL) and methanol (10 mL). The solution was stirred overnight at room temperature, then concentrated to afford the title compound as a white solid (100%). MS (ESI): 160.0 (M+H)+.
後処理
- concentrationconcentrated
出典と根拠
- ORDレコード
- ord-a9c5bc72506a4d55a442a6d12ce9db5c
- 出典データセット
- uspto-grants-1999_12
- 特許番号
- US05998470
反応ノート
読み込み中…