Hydrochloric Acid → 1-(2-dimethylaminomethyl-5,7-dihydro-4H-furo[2,3-c]pyridin-6-yl)-3-(3-phenethylphenyl)propan-1-one hydrochloride

HRID 611101ノート

反応式

HRID 611101 の反応式
[CH3:1][N:2]([CH2:4][C:5]1[O:31][C:8]2[CH2:9][N:10]([C:13](=[O:30])[CH2:14][CH2:15][C:16]3[CH:21]=[CH:20][CH:19]=[C:18]([CH2:22][CH2:23][C:24]4[CH:29]=[CH:28][CH:27]=[CH:26][CH:25]=4)[CH:17]=3)[CH2:11][CH2:12][C:7]=2[CH:6]=1)[CH3:3].[ClH:32]>CO>[ClH:32].[CH3:1][N:2]([CH2:4][C:5]1[O:31][C:8]2[CH2:9][N:10]([C:13](=[O:30])[CH2:14][CH2:15][C:16]3[CH:21]=[CH:20][CH:19]=[C:18]([CH2:22][CH2:23][C:24]4[CH:29]=[CH:28][CH:27]=[CH:26][CH:25]=4)[CH:17]=3)[CH2:11][CH2:12][C:7]=2[CH:6]=1)[CH3:3]

参加物

4

反応物 2

HCID 313Hydrochloric AcidHCID 196000521-(2-dimethylaminomethyl-5,7-dihydro-4H-furo[2,3-c]pyridin-6-yl)-3-(3-phenethylphenyl)propan-1-one

生成物 1

HCID 196002521-(2-dimethylaminomethyl-5,7-dihydro-4H-furo[2,3-c]pyridin-6-yl)-3-(3-phenethylphenyl)propan-1-one hydrochloride

試薬・触媒・溶媒 1

HCID 887Methanol溶媒2 回

実験手順

1-(2-Dimethylaminomethyl-5,7-dihydro-4H-furo[2,3-c]pyridin-6-yl)-3-(3-phenethylphenyl)propan-1-one 0.237 g was dissolved in 2 ml of methanol; hydrogen chloride in methanol was added in excess, followed by stirring. After this mixture was concentrated, diethyl ether was added; the resulting solid was filtered and washed with diethyl ether to yield the desired product.

後処理

  1. concentrationAfter this mixture was concentrated
  2. additiondiethyl ether was added
  3. filtrationthe resulting solid was filtered
  4. washwashed with diethyl ether

出典と根拠

ORDレコード
ord-325af179a641444c9dd1a62838bafa52
出典データセット
uspto-grants-1999_12
特許番号
US05998433

反応ノート

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