Hydrochloric Acid → HCID 19600238、化合物

HRID 611150ノート

反応式

HRID 611150 の反応式
[CH3:1][N:2]([CH2:4][C:5]1[O:27][C:8]2[CH2:9][N:10]([C:13](=[O:26])[CH2:14][CH2:15][CH2:16][CH2:17][CH2:18][C:19]3[CH:24]=[CH:23][C:22]([F:25])=[CH:21][CH:20]=3)[CH2:11][CH2:12][C:7]=2[CH:6]=1)[CH3:3].[ClH:28]>CO.C(OCC)(=O)C>[ClH:28].[CH3:1][N:2]([CH2:4][C:5]1[O:27][C:8]2[CH2:9][N:10]([C:13](=[O:26])[CH2:14][CH2:15][CH2:16][CH2:17][CH2:18][C:19]3[CH:24]=[CH:23][C:22]([F:25])=[CH:21][CH:20]=3)[CH2:11][CH2:12][C:7]=2[CH:6]=1)[CH3:3]

参加物

5

反応物 2

HCID 313Hydrochloric AcidHCID 19600003HCID 19600003、化合物

生成物 1

HCID 19600238HCID 19600238、化合物

試薬・触媒・溶媒 2

HCID 887Methanol溶媒HCID 8857Ethyl Acetate溶媒

実験手順

1-(2-Dimethylaminomethyl-5,7-dihydro-4H-furo[2,3-c]pyridin-6-yl)-6-(4-fluorophenyl)hexan-1-one 0.098 g was dissolved in 2 ml of methanol; hydrogen chloride in ethyl acetate was added in excess, followed by stirring. After this mixture was concentrated, the resulting solid was washed with diethyl ether to yield the desired product.

後処理

  1. concentrationAfter this mixture was concentrated
  2. washthe resulting solid was washed with diethyl ether

出典と根拠

ORDレコード
ord-6068050c85114646850f3e70977a81df
出典データセット
uspto-grants-1999_12
特許番号
US05998433

反応ノート

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