HCID 19600120、化合物 → Methyl 4,5,6,7-tetrahydrofuro[2,3-c]pyridine-2-carboxylate

HRID 611242ノート

反応式

HRID 611242 の反応式
C([N:8]1[CH2:13][CH2:12][C:11]2[CH:14]=[C:15]([C:17]([O:19][CH3:20])=[O:18])[O:16][C:10]=2[CH2:9]1)C1C=CC=CC=1>CO.[C].[Pd]>[O:16]1[C:10]2[CH2:9][NH:8][CH2:13][CH2:12][C:11]=2[CH:14]=[C:15]1[C:17]([O:19][CH3:20])=[O:18]

参加物

4

反応物 1

HCID 19600120HCID 19600120、化合物

生成物 1

HCID 19600098Methyl 4,5,6,7-tetrahydrofuro[2,3-c]pyridine-2-carboxylate

試薬・触媒・溶媒 2

HCID 178418390HCID 178418390、化合物触媒HCID 887Methanol溶媒

実験手順

A solution of 0.285 g (1.050 mmol) of methyl 6-benzyl-4,5,6,7-tetrahydrofuro[2,3-c]pyridine-2-carboxylate in 30 ml of methanol was hydrogenated at room temperature at atmospheric pressure over 0.2 g of 10% palladium-carbon (50% wet) overnight. After the catalyst was filtered off, the filtrate was evaporated under reduced pressure to yield the desired product.

後処理

  1. filtrationAfter the catalyst was filtered off
  2. customthe filtrate was evaporated under reduced pressure

出典と根拠

ORDレコード
ord-bef794c704fe44a4bed37bbfb8a46dbd
出典データセット
uspto-grants-1999_12
特許番号
US05998433

反応ノート

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