Hydrochloric Acid → HCID 19600244、化合物

HRID 611276ノート

反応式

HRID 611276 の反応式
[CH3:1][N:2]([CH2:4][C:5]1[O:13][C:12]2[CH2:11][CH2:10][N:9]([C:14](=[O:30])[C:15]3[CH:20]=[CH:19][C:18]([C:21](=[O:29])[C:22]4[CH:27]=[CH:26][C:25]([F:28])=[CH:24][CH:23]=4)=[CH:17][CH:16]=3)[CH2:8][C:7]=2[CH:6]=1)[CH3:3].[ClH:31]>CO.C(OCC)(=O)C>[ClH:31].[CH3:3][N:2]([CH2:4][C:5]1[O:13][C:12]2[CH2:11][CH2:10][N:9]([C:14](=[O:30])[C:15]3[CH:20]=[CH:19][C:18]([C:21](=[O:29])[C:22]4[CH:23]=[CH:24][C:25]([F:28])=[CH:26][CH:27]=4)=[CH:17][CH:16]=3)[CH2:8][C:7]=2[CH:6]=1)[CH3:1]

参加物

5

反応物 2

HCID 313Hydrochloric AcidHCID 19599911HCID 19599911、化合物

生成物 1

HCID 19600244HCID 19600244、化合物

試薬・触媒・溶媒 2

HCID 887Methanol溶媒HCID 8857Ethyl Acetate溶媒

実験手順

N,N-Dimethyl-[5-[4-(4-fluorobenzoyl)benzoyl]-4,5,6,7-tetrahydrofuro[3,2-c]pyridin-2-ylmethyl]amine 0.116 g was dissolved in 2 ml of methanol; hydrogen chloride in ethyl acetate was added in excess, followed by stirring. This mixture was then concentrated; the resulting solid was washed with diethyl ether to yield the desired product.

後処理

  1. concentrationThis mixture was then concentrated
  2. washthe resulting solid was washed with diethyl ether

出典と根拠

ORDレコード
ord-d1fa804895214443b55c2e6a405dd632
出典データセット
uspto-grants-1999_12
特許番号
US05998433

反応ノート

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