Hydrochloric Acid → (E)-N,N-dimethyl-[5-(2,3-diphenylpropenoyl)-4,5,6,7-tetrahydrofuro[3,2-c]pyridin-2-ylmethyl]amine hydrochloride

HRID 611346

反応式

HRID 611346 の反応式
[CH3:1][N:2]([CH2:4][C:5]1[O:13][C:12]2[CH2:11][CH2:10][N:9]([C:14](=[O:29])/[C:15](/[C:23]3[CH:28]=[CH:27][CH:26]=[CH:25][CH:24]=3)=[CH:16]/[C:17]3[CH:22]=[CH:21][CH:20]=[CH:19][CH:18]=3)[CH2:8][C:7]=2[CH:6]=1)[CH3:3].[ClH:30]>CO.C(OCC)(=O)C>[ClH:30].[CH3:1][N:2]([CH2:4][C:5]1[O:13][C:12]2[CH2:11][CH2:10][N:9]([C:14](=[O:29])/[C:15](/[C:23]3[CH:24]=[CH:25][CH:26]=[CH:27][CH:28]=3)=[CH:16]/[C:17]3[CH:18]=[CH:19][CH:20]=[CH:21][CH:22]=3)[CH2:8][C:7]=2[CH:6]=1)[CH3:3]

参加物

5

反応物 2

HCID 313Hydrochloric AcidHCID 19600147(E)-N,N-dimethyl-[5-(2,3-diphenylpropenoyl)-4,5,6,7-tetrahydrofuro[3,2-c]pyridin-2-ylmethyl]amine

生成物 1

HCID 19600146(E)-N,N-dimethyl-[5-(2,3-diphenylpropenoyl)-4,5,6,7-tetrahydrofuro[3,2-c]pyridin-2-ylmethyl]amine hydrochloride

試薬・触媒・溶媒 2

HCID 887Methanol溶媒HCID 8857Ethyl Acetate溶媒

実験手順

(E)-N,N-Dimethyl-[5-(2,3-diphenylpropenoyl)-4,5,6,7-tetrahydrofuro[3,2-c]pyridin-2-ylmethyl]amine 0.241 g was dissolved in 2 ml of methanol; hydrogen chloride in ethyl acetate was added in excess, followed by stirring. This mixture was concentrated and washed with diethyl ether to yield the desired product.

後処理

  1. concentrationThis mixture was concentrated
  2. washwashed with diethyl ether

出典と根拠

ORDレコード
ord-1c20908060a24e9a8f283d8a87b7543b
出典データセット
uspto-grants-1999_12
特許番号
US05998433

関連ノート

読み込み中…