Hydrochloric Acid → HCID 19600207、化合物

HRID 611396ノート

反応式

HRID 611396 の反応式
[CH3:1][N:2]([CH2:4][C:5]1[O:13][C:12]2[CH2:11][CH2:10][N:9]([C:14](=[O:33])[C:15]3[CH:20]=[CH:19][C:18]([C:21]4([C:27]5[CH:32]=[CH:31][CH:30]=[CH:29][CH:28]=5)[S:26][CH2:25][CH2:24][CH2:23][S:22]4)=[CH:17][CH:16]=3)[CH2:8][C:7]=2[CH:6]=1)[CH3:3].[ClH:34]>CO.C(OCC)(=O)C>[ClH:34].[CH3:3][N:2]([CH2:4][C:5]1[O:13][C:12]2[CH2:11][CH2:10][N:9]([C:14](=[O:33])[C:15]3[CH:16]=[CH:17][C:18]([C:21]4([C:27]5[CH:28]=[CH:29][CH:30]=[CH:31][CH:32]=5)[S:22][CH2:23][CH2:24][CH2:25][S:26]4)=[CH:19][CH:20]=3)[CH2:8][C:7]=2[CH:6]=1)[CH3:1]

参加物

5

反応物 2

HCID 313Hydrochloric AcidHCID 19600032HCID 19600032、化合物

生成物 1

HCID 19600207HCID 19600207、化合物

試薬・触媒・溶媒 2

HCID 887Methanol溶媒HCID 8857Ethyl Acetate溶媒

実験手順

N,N-Dimethyl-[5-[4-(2-phenyl-1,3-dithian-2-yl)benzoyl]-4,5,6,7-tetrahydrofuro[3,2-c]pyridin-2-ylmethyl]amine 0.368 g was dissolved in 2 ml of methanol; hydrogen chloride in ethyl acetate was added in excess, followed by stirring. This mixture was concentrated and washed with diethyl ether to yield the desired product.

後処理

  1. concentrationThis mixture was concentrated
  2. washwashed with diethyl ether

出典と根拠

ORDレコード
ord-99600573d6154d6d91955846042db291
出典データセット
uspto-grants-1999_12
特許番号
US05998433

反応ノート

読み込み中…