Carbon Tetrachloride → Ethyl 3-bromo-6-methoxy-2-methylbenzoate

HRID 611713

反応式

HRID 611713 の反応式
[CH3:1][C:2]1[C:7]([C:8]([O:10][CH2:11][CH3:12])=[O:9])=[C:6]([O:13][CH3:14])[CH:5]=[CH:4][CH:3]=1.[Br:15]Br.ClC(Cl)(Cl)Cl>O>[Br:15][C:3]1[CH:4]=[CH:5][C:6]([O:13][CH3:14])=[C:7]([C:2]=1[CH3:1])[C:8]([O:10][CH2:11][CH3:12])=[O:9]

参加物

5

反応物 3

HCID 5943Carbon TetrachlorideHCID 24408BromineHCID 5910602-Methoxy-6-methyl-benzoic acid ethyl ester

生成物 1

HCID 11022052Ethyl 3-bromo-6-methoxy-2-methylbenzoate

試薬・触媒・溶媒 1

HCID 962Water溶媒

実験手順

A mixture of ethyl 6-methyl-2-methoxybenzoate (8.4 g, 43.2 mmol), bromine (6.9 g, 43.2 mmol) and tetrachloromethane (170 ml) is stirred at room temperature for 60 hours. The reaction mixture is poured into water and extracted with ethyl acetate. The organic phase is separated and concentrated. The crude product is obtained as a yellow oil, 10.3 g (87%) and is used without further purification.

後処理

  1. extractionextracted with ethyl acetate
  2. customThe organic phase is separated
  3. concentrationconcentrated

出典と根拠

ORDレコード
ord-2f9fb22998714a3b940f3595d535229d
出典データセット
uspto-grants-1999_12
特許番号
US06001883

関連ノート

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