Salicylaldehyde → Salicylaldehyde thiosemicarbazone
反応式
[CH:1](=O)[C:2]1[C:3](=[CH:5][CH:6]=[CH:7][CH:8]=1)[OH:4].[NH2:10][NH:11][C:12]([NH2:14])=[S:13]>O>[CH:1](=[N:10][NH:11][C:12]([NH2:14])=[S:13])[C:2]1[C:3](=[CH:5][CH:6]=[CH:7][CH:8]=1)[OH:4]参加物
4
反応条件
- 温度
- 75 °C
実験手順
Salicylaldehyde was added dropwise over 5 min. to a solution of thiosemicarbazide (5.47 g, 60 mmol) in 75 mL water maintained at 75° C. A white solid began to precipitate immediately. The resulting mixture was heated to reflux for 2 hours, then cooled to room temperature and filtered to give salicylaldehyde thiosemicarbazone (11.5 g, 98%) as a white crystalline solid.
後処理
- customto precipitate immediately
- temperatureThe resulting mixture was heated
- temperatureto reflux for 2 hours
- temperaturecooled to room temperature
- filtrationfiltered
出典と根拠
- ORDレコード
- ord-af9ebb1461984442be34e62bb2a33691
- 出典データセット
- uspto-grants-1999_12
- 特許番号
- US06001937
反応ノート
読み込み中…