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2-Fluoro-5-(trifluoromethyl)pyridine → HCID 117727861、化合物
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | 2-Fluoro-5-(trifluoromethyl)pyridine | HCID 5463754 | — |
| 反応物 | 2-Iodo-6-methylbenzoic acid | HCID 9856531 | — |
| 反応物 | ((2S,3R)-2-(aminomethyl)-3-methylpiperidin-1-yl)(2-methyl-6-(pyrimidin-2-yl)phenyl)methanone | HCID 117728173 | — |
| 生成物 | HCID 117727861 | HCID 117727861 | — |
反応手順
The title compound was prepared following the same general protocol as described for Example A230 using 2-iodo-6-methylbenzoic acid to make ((2S,3R)-2-(aminomethyl)-3-methylpiperidin-1-yl)(2-methyl-6-(pyrimidin-2-yl)phenyl)methanone and 2-fluoro-5-(trifluoromethyl)pyridine. ESI-MS (m/z): 470 [M+1]+.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US09440982B2 |
| 出典データセット | uspto-grants-2016_09 |
| ORD ID | ord-c2bed0fb38f7421fae54e6d1dbc6f1cd |
| 出典メモ | uspto-grants-2016_09 |