tert-butyl N-(2-hydroxyethyl)carbamate → HCID 135624007、化合物

HRID 612892ノート

反応式

HRID 612892 の反応式
[OH:1][C:2]1[CH:6]=[C:5]([C:7]2[CH:12]=[CH:11][C:10]([OH:13])=[CH:9][CH:8]=2)[O:4][N:3]=1.[C:14]([O:18][C:19]([NH:21][CH2:22][CH2:23]O)=[O:20])([CH3:17])([CH3:16])[CH3:15]>>[C:14]([O:18][C:19]([NH:21][CH2:22][CH2:23][O:1][C:2]1[CH:6]=[C:5]([C:7]2[CH:12]=[CH:11][C:10]([OH:13])=[CH:9][CH:8]=2)[O:4][N:3]=1)=[O:20])([CH3:17])([CH3:16])[CH3:15]

参加物

3

反応物 2

HCID 2733206tert-butyl N-(2-hydroxyethyl)carbamateHCID 1785158765-(4-Hydroxyphenyl)isoxazol-3-ol

生成物 1

HCID 135624007HCID 135624007、化合物収率 67%

実験手順

3-Hydroxy-5-(4-hydroxyphenyl)isoxazole (0.1 g) and 2-(N-tert-butoxycarbonylamino)ethanol (0.1 g) were subjected to reaction and post-treatment in a similar manner to that described in Example 9(a) to obtain the title compound (0.12 g, 67%) as a colorless powder.

出典と根拠

ORDレコード
ord-52eb468c3c1a41f4aee3e101774af005
出典データセット
uspto-grants-1999_12
特許番号
US06005116

反応ノート

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