4-Fluoro-3-methoxymethoxy-5-phenylisoxazole → HCID 178519001、化合物

HRID 612924ノート

反応式

HRID 612924 の反応式
[F:1][C:2]1[C:3]([O:13]COC)=[N:4][O:5][C:6]=1[C:7]1[CH:12]=[CH:11][CH:10]=[CH:9][CH:8]=1>Cl.O1CCOCC1>[F:1][C:2]1[C:3]([OH:13])=[N:4][O:5][C:6]=1[C:7]1[CH:12]=[CH:11][CH:10]=[CH:9][CH:8]=1

参加物

3

反応物 1

HCID 195967054-Fluoro-3-methoxymethoxy-5-phenylisoxazole

生成物 1

HCID 178519001HCID 178519001、化合物収率 84.9%

試薬・触媒・溶媒 1

HCID 204431481,4-Dioxane hydrochloride溶媒

実験手順

4-Fluoro-3-methoxymethoxy-5-phenylisoxazole (0.44 g) was dissolved in a solution of 4N hydrochloric acid/dioxane (5.0 ml), and the solution was stirred at room temperature for one hour. After the reaction, the solvent was evaporated under reduced pressure and the crystal thus obtained was washed with dichloromethane (10 ml) to obtain the title compound (0.30 g, 83%) as colorless crystals.

後処理

  1. customAfter the reaction
  2. customthe solvent was evaporated under reduced pressure
  3. customthe crystal thus obtained
  4. washwas washed with dichloromethane (10 ml)

出典と根拠

ORDレコード
ord-3a43b3fe7e1247b4bd4d2510ffd293a6
出典データセット
uspto-grants-1999_12
特許番号
US06005116

反応ノート

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