HCID 19596499、化合物 → 3-(2-Dimethylaminoethoxy)-5-phenylisoxazole hydrochloride
反応式
[CH3:1][N:2]([CH3:17])[CH2:3][CH2:4][O:5][C:6]1[CH:10]=[C:9]([C:11]2[CH:16]=[CH:15][CH:14]=[CH:13][CH:12]=2)[O:8][N:7]=1.[ClH:18].O1CCOCC1>O1CCOCC1>[ClH:18].[CH3:1][N:2]([CH3:17])[CH2:3][CH2:4][O:5][C:6]1[CH:10]=[C:9]([C:11]2[CH:16]=[CH:15][CH:14]=[CH:13][CH:12]=2)[O:8][N:7]=1参加物
4
実験手順
3-(2-Dimethylaminoethoxy)-5-phenylisoxazole (130 mg) was dissolved in dioxane (1.0 ml), and a solution of 4N hydrochloric acid/dioxane (0.2 ml) was added thereto, and the resulting mixture was allowed to stand at room temperature for 15 minutes. The solvent was evaporated under reduced pressure and the residue was washed with ethyl acetate (5 ml) to obtain the title compound (148 mg, 98%) as colorless crystals.
後処理
- customThe solvent was evaporated under reduced pressure
- washthe residue was washed with ethyl acetate (5 ml)
出典と根拠
- ORDレコード
- ord-5017179cea2943169bd51fcbc8fb9bad
- 出典データセット
- uspto-grants-1999_12
- 特許番号
- US06005116
反応ノート
読み込み中…