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HRID 61295作成日:2026年10月26日

(S)-Benzyl 2-amino-3-methoxypropanoate hydrochloride → (S)-2-((S)-2-tert-butoxycarbonylamino-3-difluoromethoxy-propionylamino)-3-methoxy-propionic acid benzyl ester

https://huagongshe.com/reaction/61295

反応式

関与物質

役割名称HCID仕込み量
反応物(S)-Benzyl 2-amino-3-methoxypropanoate hydrochlorideHCID 69153484—
反応物(S)-2-tert-Butoxycarbonylamino-3-difluoromethoxy-propionic acidHCID 86709693—
生成物(S)-2-((S)-2-tert-butoxycarbonylamino-3-difluoromethoxy-propionylamino)-3-methoxy-propionic acid benzyl esterHCID 90040871—

反応手順

The compound of Formula II(b)(ii) was prepared as an off-white foam in a similar manner as the compound of Formula II(a)(ii), described above, from the compound of Formula IV(a), (S)-2-tert-butoxycarbonylamino-3-difluoromethoxy-propionic acid and the compound of Formula V(b), (S)-2-amino-3-methoxy-propionic acid benzyl ester, hydrochloride salt.

情報源と証拠

DOI10.6084/m9.figshare.5104873.v1
特許番号US09441012B2
出典データセットuspto-grants-2016_09
ORD IDord-8c426d448f92404ea77365e923e04078
出典メモuspto-grants-2016_09