(3-Chloropropyl)benzene → N-(4-Hydroxy-2-oxo-6-phenyl-2H-pyran-3-yl)benzenepropanamide

関与物質

反応手順

The title compound was prepared by Method E using 3-amino-4-hydroxy-6-phenyl-2H-pyran-2-one hydrochloride (0.150 g, 0.626 mmol), THF (6 mL), 60% sodium hydride (0.028 mL, 0.688 mmol), hydrocinnamyl chloride (0.131 g, 0.688 mmol). m.p. 191-193° C.; 1H NMR (250 MHz, DMSO-d6) δ2.65 (t, 2 H), 2.89 (t, 2 H), 6.86 (s, 1 H), 7.26 (m, 5 H), 7.53 (m, 3 H), 7.84 (m, 2 H), 9.28 (s, 1 H).

情報源と証拠