Isoprene → 4-Cyclohexene-1,2-dicarboxylic acid, 4-methyl-, dimethyl ester

HRID 61342

反応式

HRID 61342 の反応式
[CH2:1]=[CH:2][C:3](=[CH2:5])[CH3:4].[C:6]([O:14][CH3:15])(=[O:13])/[CH:7]=[CH:8]\[C:9]([O:11][CH3:12])=[O:10]>>[CH3:12][O:11][C:9]([CH:8]1[CH2:1][CH:2]=[C:3]([CH3:5])[CH2:4][CH:7]1[C:6]([O:14][CH3:15])=[O:13])=[O:10]

参加物

3

反応物 2

HCID 6557IsopreneHCID 5271565Dimethyl maleate

生成物 1

HCID 2743794-Cyclohexene-1,2-dicarboxylic acid, 4-methyl-, dimethyl ester収率 66.7%

反応条件

温度
150 °C

実験手順

Isoprene (350 g, 5.1 mol) and dimethyl maleate (741 g, 5.1 mol) were loaded into a stainless steel autoclave. The autoclave was sealed and heated to 150° C. The temperature of the autoclave increased to 195° C. due to the heat of the reaction. The temperature was held at 160° C. for 1 hour. Gas chromatography (GC) analysis indicated the completion of the reaction. The autoclave was then cooled to room temperature. Simple distillation of the resulting mixture provided 4-methyl-cyclohex-4-ene-1,2-dicarboxylic acid dimethyl ester (725 g, 3.4 mol, 66% yield) as a light yellow liquid.

後処理

  1. customThe autoclave was sealed
  2. temperatureThe temperature of the autoclave increased to 195° C. due to the
  3. temperatureheat of the reaction
  4. customthe completion of the reaction
  5. temperatureThe autoclave was then cooled to room temperature
  6. distillationSimple distillation of the resulting mixture

出典と根拠

ORDレコード
ord-eba05cae420d4eb5ae930194eb321a31
出典データセット
uspto-grants-2016_09
特許番号
US09441185B2

関連ノート

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