Hydrochloric Acid → HCID 178492409、化合物

HRID 613954ノート

反応式

HRID 613954 の反応式
[NH2:1][C:2]1[C:3]([OH:12])=C2[C:8](=[N:9][C:10]=1[CH3:11])[NH:7][N:6]=N2.[CH3:13][N:14](C)C1C=CC=CC=1.[CH3:22][O:23][C:24]1[CH:29]=[CH:28][C:27]([N:30]=[N:31][C:32]2[CH:40]=[C:36]([C:37](Cl)=[O:38])[C:35]([OH:41])=[CH:34][CH:33]=2)=[CH:26][CH:25]=1.Cl>CN(C)C=O>[OH:41][C:35]1[CH:34]=[CH:33][C:32]([N:31]=[N:30][C:27]2[CH:28]=[CH:29][C:24]([O:23][CH3:22])=[CH:25][CH:26]=2)=[CH:40][C:36]=1[C:37]([NH:1][C:2]1[C:10]([CH3:11])=[N:9][C:8]2[N:7]([N:6]=[CH:13][N:14]=2)[C:3]=1[OH:12])=[O:38]

参加物

6

反応物 4

HCID 313Hydrochloric AcidHCID 949N,N-DimethylanilineHCID 1355740405-(4-Methoxyphenylazo)salicoyl chlorideHCID 178432419HCID 178432419、化合物

生成物 1

HCID 178492409HCID 178492409、化合物

試薬・触媒・溶媒 1

HCID 6228Dimethylformamide溶媒

実験手順

5-Amino-4-hydroxy-6-methyltetraazaindene (0.5 g) was dissolved in dry N,N-dimethylformamide (10 ml) and dimethylaniline (0.37 g) added. 5-(4-Methoxyphenylazo)salicoyl chloride (0.88 g) was added portionwise at room temperature with stirring. After 12 hours the mixture was poured into iced dilute hydrochloric acid and the crude product collected, washed with water and dried. The material was extracted with a large volume of ether and crystallized in aqueous ethanol as the monohydrate (0.8 g, 61%), m.p. 323°-324° decomp., λmax (methanol) = 354 nm.

後処理

  1. customthe crude product collected
  2. washwashed with water
  3. customdried
  4. extractionThe material was extracted with a large volume of ether
  5. customcrystallized in aqueous ethanol as the monohydrate (0.8 g, 61%), m.p. 323°-324° decomp., λmax (methanol) = 354 nm

出典と根拠

ORDレコード
ord-a4ee5ce9d0df4926b44ee18bc694f457
出典データセット
uspto-grants-1979_03
特許番号
US04142901

反応ノート

読み込み中…