HCID 21330005、化合物 → HCID 21330002、化合物

反応式

C([NH:11][CH:12]([C:14]1[C:23]2[C:18](=[CH:19][C:20]([O:26][CH3:27])=[C:21]([O:24][CH3:25])[CH:22]=2)[CH2:17][CH2:16][N:15]=1)[CH3:13])(OCC1C=CC=CC=1)=O.[BrH:28].C(O)(=O)C>>[BrH:28].[BrH:28].[NH2:11][CH:12]([C:14]1[C:23]2[C:18](=[CH:19][C:20]([O:26][CH3:27])=[C:21]([O:24][CH3:25])[CH:22]=2)[CH2:17][CH2:16][N:15]=1)[CH3:13]

参加物

反応物 2

HCID 21330005HCID 21330005、化合物

HCID 21893785Acetic Acid Mixture with Hydrobromic Acid

生成物 1

HCID 21330002HCID 21330002、化合物

実験手順

40 g 1-(1-carbobenzoxyaminoethyl)-3,4-dihydro-6,7-dimethoxyisoquinoline are dissolved in 450 ml 40% HBr/acetic acid. The mixture is maintained at room temperature for 1 hour and then concentrated in a vacuum to give a crystalline residue of 1-(1-aminoethyl)-3,4-dihydro-6,7-dimethoxyisoquinoline dihydrobromide which is washed with ether before further use (M.Pt. 234°-235°).

後処理

concentrationconcentrated in a vacuum

出典と根拠

ORDレコード: ord-ab217360f72044cd84b88f326ff6e7ac
出典データセット: uspto-grants-1979_03
DOI: 10.6084/m9.figshare.5104873.v1
特許番号: US04143143

反応ノート

読み込み中…

参加物