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tert-Butyl 2-bromo-2-methylpropionate → 2-(2-t-Butoxycarbonylprop-2-yloxyimino)-2-(thien-2-yl)acetic acid
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | tert-Butyl 2-bromo-2-methylpropionate | HCID 90290 | — |
| 反応物 | Benethamine(1+) | HCID 1549262 | — |
| 反応物 | 2-Hydroxyimino(thien-2-yl)acetic acid | HCID 73629644 | — |
| 溶媒 | Ethanol | HCID 702 | — |
| 生成物 | 2-(2-t-Butoxycarbonylprop-2-yloxyimino)-2-(thien-2-yl)acetic acid | HCID 54300039 | 78% |
反応手順
The title compound was prepared from 2-hydroxyimino-2-(thien-2-yl)acetic acid (syn isomer) and t-butyl 2-bromo-2-methylpropionate, in a similar manner to that described for Preparation 1, in 78% yield as a colourless oil, and was characterised as the N-benzyl-2-phenylethylammonium salt, m.p. 201.3°-201.9° (from ethanol).
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US04144393 |
| 出典データセット | uspto-grants-1979_03 |
| ORD ID | ord-2f0fb51db1684aecb32016f21778516f |
| 出典メモ | uspto-grants-1979_03 |