Methyl 2-oxo-4-phenyl-1-pyrrolidineacetate → N-[3-[bis(1-methylethyl)amino]propyl]-2-oxo-4-phenyl-1-pyrrolidineacetamide

HRID 614470ノート

反応式

HRID 614470 の反応式
[O:1]=[C:2]1[CH2:6][CH:5]([C:7]2[CH:12]=[CH:11][CH:10]=[CH:9][CH:8]=2)[CH2:4][N:3]1[CH2:13][C:14]([O:16]C)=O.[CH:18]([N:21]([CH:26]([CH3:28])[CH3:27])[CH2:22][CH2:23][CH2:24][NH2:25])([CH3:20])[CH3:19]>>[CH3:20][CH:18]([N:21]([CH:26]([CH3:28])[CH3:27])[CH2:22][CH2:23][CH2:24][NH:25][C:14](=[O:16])[CH2:13][N:3]1[CH2:4][CH:5]([C:7]2[CH:8]=[CH:9][CH:10]=[CH:11][CH:12]=2)[CH2:6][C:2]1=[O:1])[CH3:19]

参加物

3

反応物 2

HCID 13684993Methyl 2-oxo-4-phenyl-1-pyrrolidineacetateHCID 13802779N~1~,N~1~-Di(propan-2-yl)propane-1,3-diamine

生成物 1

HCID 44374749N-[3-[bis(1-methylethyl)amino]propyl]-2-oxo-4-phenyl-1-pyrrolidineacetamide

実験手順

From 6.2 g. of methyl 2-oxo-4-phenylpyrrolidineacetate and 8.0 g. of 3-(diisopropylamino)propylamine [J.A.C.S. 65, 2012 (1943)], following the procedure of Example 1, there is obtained N-[3-[bis(1-methylethyl)amino]propyl]-2-oxo-4-phenyl-1-pyrrolidineacetamide in pure form as an oil, without need for distillation.

出典と根拠

ORDレコード
ord-1fcb204ab4da4165965ccf7e37d40819
出典データセット
uspto-grants-1979_03
特許番号
US04145347

反応ノート

読み込み中…